Fioricet contains a combination of acetaminophen, butalbital, and caffeine. Butalbital is a short to intermediate-acting barbiturate and is habit-forming and potentially abusable. Consequently, the extended use of this product is not recommended.
Acetaminophen is used to relieve mild to moderate pain from headaches, muscle aches, menstrual periods, colds and sore throats, toothaches, backaches, and reactions to vaccinations (shots), and to reduce fever. Caffeine is a methylxanthine similar to theophylline and theobromine. While caffeine is used for stimulant and mood-elevating effects in drinks such as coffee, it also has been used to treat neonatal apnea and headaches in combination with other analgesics.
Following image is the ingredient of fioricet.
The average daily dose for the barbiturate addict is usually about 1500 mg. But the lethal dose of a barbiturate is far less if alcohol is also ingested. It is strictly required not taking alcohol while you are taking fioricet. One of the important ingredient is acetaminophen. A lot of drugs contains acetaminophen.
More than 600 medicines contain acetaminophen. These medicines include both prescription medicines and OTC medicines. On prescription labels, acetaminophen is sometimes listed as “APAP,” “acetam,” or other shorted versions of the word. Please read very carefully when you are taking the medicines that contains APAP because overdose of acetaminophen will hurt your heart, liver, and kidney seriously. To know what is in your medicines, read the list of active ingredients on the label each and every time you take a medicine. Following picture is a list of some OTC or prescription drugs that contain acetaminophen.
When you take drugs for pain relief. Please check whether the drug contains apap. You cannot take more than 4000mg acetaminophen per day.
Liver Damage While taking Acetaminophen
The safety dosage is 3000mg per day. Acetaminophen has been associated with cases of acute liver failure, at times resulting in liver transplant and death. Most of the cases of liver injury are associated with the use of acetaminophen at doses that exceed 4000 milligrams per day, and often involve more than one acetaminophen-containing product. According to the FDA, in the United States there were “56,000 emergency room visits, 26,000 hospitalizations, and 458 deaths per year related to acetaminophen-associated overdoses during the 1990s. Within these estimates, unintentional acetaminophen overdose accounted for nearly 25% of the emergency department visits, 10% of the hospitalizations, and 25% of the deaths.” 
Before taking this medicine
Do not use Fioricet if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.
You should not use Fioricet if you are allergic to acetaminophen, butalbital, or caffeine, if you have porphyria, or if you have recently used alcohol, sedatives, tranquilizers, or other narcotic medications.
To make sure Fioricet is safe for you, tell your doctor if you have:
- liver disease, cirrhosis, a history of alcoholism or drug addiction, or if you drink more than 3 alcoholic beverages per day;
- kidney disease;
- asthma, sleep apnea, or other breathing disorder;
- stomach ulcer or bleeding;
- a history of skin rash caused by any medication;
- a history of mental illness or suicidal thoughts; or
- if you use medicine to prevent blood clots.
It is not known whether Fioricet will harm an unborn baby. If you use butalbital while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks. Tell your doctor if you are pregnant or plan to become pregnant.
This medicine can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby.